Many people from some countries such as Korea, USA, China, Indonesia, Australia, Singapore, and Vietnam have been taking Botamedi health supplements for the brain recovery. About 80% patients among them have found that up to 80% of the damaged function was improved in 12 months and there was no side-effects due to the products. Since US-FDA approved Botamedi marine bio-phenol as IND (investigational new drug) in 2013, BotaMedi research group has developed the botanical medicine for the brain recovery. On the other hand, US-FDA has already notified Botamedi marine bio-phenol as NDI (new dietary ingredient) in 2008, which means it's so safe enough to be used for the dietary ingredient in US market.  Also Korea-FDA approved this material as the new functional ingredient for lowering the high cholesterol content in blood in 2012 after human clinical trials for 3 years.